Splash Girls: Qureate announces a game where you vaccinate giant anime girls

Qureate's New 3D Action Game Puts You in Charge of Curing Virus-Infected Giant Girls With a Vaccine Gun

Studio Qureate, the Japanese developer behind the surprise hit Bunny Garden and the recently announced Filthy Room Girlfriend Project, revealed its newest title during the Qureate Digest 2026-2027 showcase held at the end of February 2026.

The game is called Splash Girls, and the premise is exactly as wild as you would expect from this studio: a group of girls have grown to gigantic size after being infected by a mysterious virus, and your job is to cure them by wielding a vaccine-firing gun and an oversized syringe. It is a third-person shooting action game coming to Nintendo Switch and PC in 2026.

The showcase, which aired in Japan in late February, also confirmed Bunny Garden 2 for spring 2026, the roguelite deckbuilder Tokyo Valkyries, and the Filthy Room Girlfriend Project, a game where players clean up their virtual girlfriend’s disastrously messy apartment, slated for 2027. Qureate has been on an aggressive release schedule, and Splash Girls is shaping up to be the most ambitious entry in their growing lineup.

A rescue mission unlike any other

Based on early details, Splash Girls positions itself as an action-heavy experience built around the exaggerated scale of its premise. Players take control of what appears to be a nurse-type character and use specialized equipment, the vaccine gun and the massive syringe, to subdue and treat the infected girls. Qureate themselves described it as an “exhilarating shooting action game,” and the game carries the descriptor “giant girls domination” in its early promotional materials.

The framing is important here: each mission is presented not as a combat scenario but as a large-scale rescue operation. The goal is to cure the girls, not defeat them, which gives the game a distinct identity even within its obviously outrageous premise. It is also a notable genre shift for Qureate, a studio primarily known for character-driven visual novel and adventure titles.

A 3D third-person shooter is a significantly more technical undertaking than anything they have released before, and that alone makes Splash Girls worth watching as development progresses.

No release date beyond the 2026 window has been confirmed. A full trailer and detailed gameplay footage have not been shared yet, meaning specifics around how the combat system works, how many infected heroines are in the game, and what the full story looks like beyond the virus outbreak setup are still to be revealed. The title is also still listed as tentative, so even the name Splash Girls could change before launch.

The studio that keeps raising the bar for bizarre concepts

To understand how Splash Girls exists, it helps to understand what Qureate has built since the studio was founded in 2018. Led by producer Yujiro Usuda, a veteran of D3 Publisher where he worked on titles like Bullet Girls and Omega Labyrinth, Qureate has spent years carving out a very specific niche in the Japanese indie gaming market, fan-service-forward titles with genuine production value and enough mechanical depth to back up their outlandish concepts.

The studio’s biggest success to date is Bunny Garden, a hostess club dating sim released in April 2024 for Nintendo Switch and PC. The game immediately topped Steam’s best sellers chart in Japan and landed at number two on the Nintendo eShop’s digital rankings upon release. It went on to earn Very Positive reviews on Steam and became widely popular among VTubers, which amplified its reach well beyond the usual audience for this type of game.

Splash Girls: Qureate announces a game where you vaccinate giant anime girls

That success opened the door to a more ambitious slate. The Qureate Digest 2026-2027 showcase made the scope of that ambition very clear: Bunny Garden 2 arrives in spring 2026, bringing back fan-favorite heroines Kana, Rin, and Miuka alongside new character Erisa, voiced by Yukina Shuto. Tokyo Valkyries delivers a roguelite deckbuilder set against a Tokyo under supernatural threat.

The Filthy Room Girlfriend Project challenges players to clean up their anime girlfriend’s genuinely catastrophic living space. And sitting at the center of all of it is Splash Girls, a game that represents the farthest Qureate has ever pushed both its concept and its technical ambitions in a single project.

What has defined Qureate across all of these releases is that the studio commits fully to whatever premise it sets out with. Bunny Garden was not a lazy cash grab riding a gimmick, it shipped with voice acting, well-developed characters, and enough gameplay systems to justify the time investment, which is exactly why it resonated with players the way it did.

There is no reason to expect Splash Girls to be handled any differently, especially given how much more technically demanding a 3D action shooter is compared to anything the studio has done before.

The game is currently in development for Nintendo Switch and PC, with a 2026 release window.

So, would you actually play a game about vaccinating giant anime girls, or has Qureate officially lost the plot? Drop your take in the comments!